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Lupus Patients At Elevated Risk For Serious Heart Disease

Jason Phillippe by Jason Phillippe
January 16, 2025
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Lupus Patients At Elevated Risk For Serious Heart Disease

Photo by Matthew Tkocz on Unsplash

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Doctors are issuing a warning.

A recent study has revealed that people with skin-related lupus have an increased risk of developing heart disease linked to the hardening of arteries. Researchers found that individuals with lupus symptoms affecting the skin are 72% more likely to develop atherosclerotic heart disease, which causes arteries to become clogged and less flexible. This finding, published in JAMA Dermatology, suggests that lupus patients with skin issues should be closely monitored for cardiovascular health.

Lupus is a chronic autoimmune disorder that causes inflammation throughout the body, affecting various organs, joints, and the skin. The most common form of lupus, known as systemic lupus erythematosus, has been previously connected to a higher risk of heart disease. However, it was not clear whether people with cutaneous lupus, which only impacts the skin, shared the same heart health risks. Past research had shown increased risks of metabolic syndrome and cancer among those with cutaneous lupus, but cardiovascular risks had not been as thoroughly examined.

In this study, researchers compared more than 8,100 people with cutaneous lupus, over 25,000 with systemic lupus, approximately 192,500 with psoriasis, and nearly 81,400 healthy individuals. Data from an insurance claims database, spanning from 2018 to 2020, was analyzed. The results showed that while systemic lupus posed the highest risk for heart disease, more than doubling the risk compared to healthy individuals, cutaneous lupus still increased the risk by 72%.

The research team recommended that healthcare providers consider the heart health risks associated with cutaneous lupus. They suggested that clinicians advise patients on adopting a heart-healthy lifestyle, including a proper diet, exercise, and avoiding smoking. Regular blood pressure and cholesterol monitoring, along with timely treatment, should also be prioritized for individuals with cutaneous lupus to manage their cardiovascular health effectively.

This study highlights the importance of considering heart disease risks in lupus patients, even those with only skin involvement. The findings encourage further research and more comprehensive screening for cardiovascular issues among people with lupus, ultimately aiming for better prevention and management of heart health in this population.

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