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The Medicine That Increases Migraine Risk

Jason Phillippe by Jason Phillippe
April 25, 2024
in Lifestyle
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The Medicine That Increases Migraine Risk

Christopher Dart, CC BY 2.0 , via Wikimedia Commons

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This is a surprising connection.

A recent study alerts that individuals using medications for heartburn face an elevated risk of experiencing migraines and severe headaches. Findings indicate that all categories of acid-reducing drugs, including proton pump inhibitors, H2 blockers, and antacids, contribute to this heightened risk.

Margaret Slavin, an associate professor at the University of Maryland, stresses the need for further investigation into the implications of acid-reducing drugs on migraines, especially considering their widespread usage and potential risks. These medications, often deemed overprescribed, have been associated with various adverse effects, such as an increased risk of dementia with prolonged use of proton pump inhibitors.

Acid reflux, characterized by the backward flow of stomach acid into the esophagus, is a common condition that can lead to heartburn, ulcers, and in severe cases, esophageal cancer. Acid-reducing drugs like proton pump inhibitors (Prevacid, Prilosec, Nexium), H2 blockers (Tagamet, Pepcid, Axid), and antacids (Mylanta, Rolaids, Tums) are commonly prescribed to manage these symptoms.

Analyzing data from nearly 12,000 individuals using acid-reducing drugs, researchers found that:

  • Proton pump inhibitors were associated with a 70% higher likelihood of experiencing migraines.
  • H2 blockers increased migraine risk by 40%.
  • Antacids raised the risk of migraines by 30%.

It’s crucial to note that the study focused solely on prescription medications and did not include over-the-counter drugs, which typically have lower potency. Slavin emphasizes the importance of consulting a healthcare professional before discontinuing acid-reducing medications.

Published in the journal Neurology on April 24, these findings underscore the necessity for individuals with acid reflux or related conditions who are also prone to migraines to discuss their treatment options with their healthcare providers. While acid-reducing medications may be necessary for managing acid reflux symptoms, it’s essential to weigh the potential risks and benefits in each individual case.

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