Miracle Weight-Loss Drug Linked To “Prematurely Aged” Look
As with most weight-loss treatments, physical transformations are expected, but some effects from popular injectable medications like Ozempic are catching users off guard. Rapid weight loss linked to semaglutide-based drugs has brought about noticeable cosmetic concerns, including what’s being called “Ozempic face,” “Ozempic feet,” and now, “Ozempic mouth.” These unintended side effects are causing growing concern among both users and medical professionals.
Dr. Ed Robinson, a leading aesthetic physician in the UK, has observed an increase in such facial changes due to fast fat loss from the lower face. He explained that “Ozempic mouth” refers to a hollow, aged look that develops around the mouth, caused by volume loss in the cheeks and jawline. This can result in features like sagging jowls, deeper lines around the mouth, and downturned lips, making patients appear tired or older than they are. In some cases, a gummy smile may also become more pronounced, especially when combined with thinning lips.
Dr. Michele Green, a cosmetic dermatologist based in New York, added that this type of facial volume loss not only introduces new aesthetic changes but may also exaggerate existing wrinkles and sagging skin. These shifts in appearance tend to be especially stark in individuals who shed large amounts of weight in a short time, as the skin often cannot adapt quickly enough to the changes in facial structure.
High-profile figures like Sharon Osbourne, Rebel Wilson, Whoopi Goldberg, and Harvey Fierstein have all shown visible signs of such side effects, according to experts. Fierstein, who reportedly lost 120 pounds using a similar drug called Zepbound, has been candid about the excess skin and jowling that followed.
To address these effects, many people are turning to cosmetic solutions such as dermal fillers. These injectable treatments help replenish lost volume, smooth wrinkles, and provide a more refreshed, youthful look. However, they can be expensive and aren’t considered a permanent fix for the aesthetic downsides of rapid weight loss associated with semaglutide medications.
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